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Amphotericin B Nephrotoxicity

Dr K Shahid, Medical Resident

University of Toronto

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Naga
Naga
January 04, 2010
99.253.107.119
Votes: +0

Hi Shahid!!

Great presentation.

I had seen a similar case in the ICU recently.
A young GP was transfered from North with acute resp distress.As you would imagine she was been treated for H1N1. But she was repeatedly negative for H1N1. She was followed by every possible service and empirically started her on Ampho B.
She was healthy otherwise with normal renal function.
But we also ruled out PE 2 days prior to ampho B.

She developed AKI...likely due to Ampho B.( with hypokalemia,Hypomagnesemia).
Lyposomal Ampho B was sugggested.......

But in the absence of positive culture,development of AKI, our Nephro team suggested to DC Ampho B.

And she recovered on her own from AKI.

Also from resp distress NYD.


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