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Pregnancy within 1 year of kidney transplantation does not affect graft survival
Pregnancy within 1 year of kidney transplantation does not affect graft survival
Nature Clinical Practice Nephrology 4, 469 (2008). doi:10.1038/ncpneph0875
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ACE gene polymorphism and the prognosis and treatment of overt diabetic nephropathy
ACE gene polymorphism and the prognosis and treatment of overt diabetic nephropathy
Nature Clinical Practice Nephrology 4, 472 (2008). doi:10.1038/ncpneph0896
Authors: Jesús Egido
& Alberto Ortiz
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Autosomal dominant polycystic kidney disease can be associated with lung abnormalities
Autosomal dominant polycystic kidney disease can be associated with lung abnormalities
Nature Clinical Practice Nephrology 4, 467 (2008). doi:10.1038/ncpneph0872
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Mycophenolate mofetil is a less toxic treatment for primary glomerulonephritis
Mycophenolate mofetil is a less toxic treatment for primary glomerulonephritis
Nature Clinical Practice Nephrology 4, 467 (2008). doi:10.1038/ncpneph0889
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Pulmonary Hypertension, Right Ventricular Failure, and Kidney: Different from Left Ventricular Failure?
In this article, the pathophysiology of left ventricular failure is reviewed. By contrast, the paucity of information about pulmonary arterial hypertension and right ventricular failure is acknowledged. The potential mechanisms whereby renal sodium and water retention in right ventricular failure secondary to pulmonary arterial hypertension can occur, despite normal left ventricular function, are discussed. With right ventricular failure as the primary cause of death in patients with pulmonary hypertension, more information about the mechanisms of renal sodium and water retention in these patients is direly needed. Specifically, studies to examine the activation of the neurohumoral axis at various stages of pulmonary arterial hypertension and right ventricular failure, including inhibition of mineralocorticoid and V2 vasopressin receptors, are indicated.
