Is there any negative consequence in having a PH = 8 showing on my Blood test.
I assume is due to the fact, that I am taking two K-CITRA 10 tablets on a daily basis.
Also is Lipitor a safe medication, to take, to prevent fatty liver condition?
At the end of 2011, Novartis suspended the ALTITUDE Study, effectively ending the possibility that the direct renin inhibitor (DRI) Aliskiren will play a significant role in the management of patients with CKD already on an ACE or ARB. This developme ...
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I have stage 3-4 CKD and I have very SEVERE arthritis. I have had both hips, knees and 1 shoulder replaced. Now I have severe aarthritis in my elbows and hands. Can I use topical Nsaid cremes or marijuana cremes?...
Hi Dr. Weinstein,
My hospital has recently made this assay available on our hospital. What is the utility of it? Does it really add much to the clinical assessment of a patient with ARF?...
Chronic kidney disease (CKD) is common, harmful, and treatable. How to evaluate your local area about CKD How to compare your local and Japanese national Incidence of Dialysis
Hello,Yes, I believe Aliskiren is a very safe medication. Over 200,000 patient-years of data have been collected and it has adverse event rates similar to placebo, similar to ARBs. It is not a concern using this drug in monotherapy, but rather combin
Hi,I agree with you. For persistent proteinuria above 1g per day despite a single RAS blocking agent, I also use supramaximal dosing or combination therapy for glomerulonephritis.
If the patient is not in steady state, the 24 hr urine is not valid.
Your question about salt restriction is an excellent one. It's controversial (despite what nutritional authorities say) that salt restriction is important for blood pressure reduction. In fact, there is little prospective data that it matters for the general population. However, ...
What if the patient is not in steady state?
If the intake is equal to the output, and your kidneys lose whatever you take, whay do we restrict salt intake?...
Hr. Samih,
By definition, in steady state, the kidney will excrete what one eats. Yes, the kidney reabsorbs 99% of filtered sodium but that amounts to roughly 20,000 mmol per day filtered and only, say 100-200 excreted (depending on what one eats). A 24 hour urine is the gold standard for measuring sodium intake. I think it is superior to an est...
Hi Dr. Kapoor,I wouldn't expect this is going to be formally tested. The above studies (particularly ALTITUDE and the rest of Aliskiren's ASPIRE portfolio) likely will suffice to disuade people from aggressively lowering MAU simply for cardioprotecti