No hyponatremia modification in asymptomatic hyponatremia

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Current total funding for this study: $523,499


Joel Topf

Study Acronym:


Hospitalized patients with a sodium between 125 and 130 would be randomized to either active treatment to restore a normal sodium or no treatment. These patients would then be followed for the following year on the same protocol with the active arm continuing to get interventions to correct the sodium while the control arm would not have the sodium actively modified.

The outcomes are: mortality, hospitalization, quality of life, falls, bone mineral density, and cost of care. Analysis would be by intention to treat, with a goal of finding non­inferiority of no treatment.

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