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Dr. Anita Hill, a hematologist with extensive expertise in the management of PNH and aHUS/TTP using eculizumab shares with us an outstanding lecture on Primary Thrombotic Microangiopathies and the Role of Complement.

Complement dysregulation is an important process in the pathophysiology of atypical HUS/TTP. Targeting this important mechanistic step with eculizumab - a novel antibody against a terminal complement protein - might have an important role in the management of this rare and challenging clinical problem.

Launch Lecture
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  1.   02 December 2019
  2.   Thrombotic Microangipathy

Presenter: Catherine M Broome MD

broome

Dr. Broome is a Board Certified Hematologist, and Associate Professor of Medicine at Georgetown University in Washington, DC. Her background and publications are in coagulation and complement systems, with a focus on consulting, diagnosing and managing Hematology Rare Diseases.

She is an internationally recognized speaker in PNH and aHUS as well. 

  1.   02 December 2019
  2.   Thrombotic Microangipathy

Presenter: Catherine M Broome MD

broome

Dr. Broome is a Board Certified Hematologist, and Associate Professor of Medicine at Georgetown University in Washington, DC. Her background and publications are in coagulation and complement systems, with a focus on consulting, diagnosing and managing Hematology Rare Diseases.

She is an internationally recognized speaker in PNH and aHUS as well. 

  1.   02 December 2019
  2.   Thrombotic Microangipathy

Presenter: Christoph Licht MD

clicht

Christoph Licht is a Paediatric Nephrologist. He is Associate Professor of Paediatrics at the University of Toronto, Ontario, Canada, Staff in the Division of Nephrology and Director of the Dialysis/Apheresis Unit of The Hospital for Sick Children in Toronto, as well as Senior Associate Scientist in the Cell Biology Program of the SickKids Research Institute. Christoph obtained his clinical training in Paediatrics and Paediatric Nephrology at the Children's Hospital of the University of Cologne, Germany, and completed his Habilitation at the University of Cologne in 2005. From 1999 to 2002 he completed a postdoctoral research fellowship in Nephrology with Bob Alpern at the University of Texas Southwestern Medical Center in Dallas, Texas, USA.

Christoph’s research focuses on complement-mediated renal diseases, in particular atypical haemolytic uraemic syndrome (aHUS) and membranoproliferative glomerulonephritis (MPGN)/C3 Glomerulopathy (C3G). He established a translational research programme including an international registry of patients with complement-mediated renal diseases (www.kidcom.ca), and an active lab studying the interactions of the complement, coagulation and inflammation systems with the vascular endothelium in the pathogenesis of aHUS. Additional research interests include the mechanisms of chronic kidney disease.

Amongst others, Christoph is the chair of HUS International (the former European Paediatric Research Group for HUS), and chair of the International aHUS Registry. He serves on the editorial board of Kidney International, Nephrology Dialysis and Transplantation and Pediatric Nephrology, and published numerous peer-reviewed articles and book chapters related to his research focus.

  1.   02 December 2019
  2.   Thrombotic Microangipathy

Presenter: Christopher Patriquin MD

CP CET

Dr. Christopher Patriquin received his MD from the University of Western Ontario, where he also completed his Internal Medicine residency. He attended McMaster University for his Haematology fellowship, where he stayed on as a Clinical Scholar in complement- mediated disease. His clinical interests include the thrombotic microangiopathies (TMA) and paroxysmal nocturnal haemoglobinuria (PNH), and his M.Sc. in Health Research Methodology focused on effective trial and observational methods in rare diseases.

In 2015, Dr. Patriquin completed honorary clinical research fellowships in the United Kingdom in TMA (University College London) and PNH (NHS National PNH Service, St. James Hospital, Leeds).

Dr. Patriquin is currently a member of the Canadian Apheresis Group TMA working group. In 2016, he joined the University Health Network Apheresis Unit.

  1.   02 December 2019
  2.   Thrombotic Microangipathy
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