Negative Result: Indicates a free water deficit. The calculated value represents the amount of free water needed to correct the hypernatremia. Treatment should be administered gradually to prevent rapid changes in serum sodium.
Positive Result: Indicates water excess. This suggests the need for water restriction or other interventions to correct hyponatremia.
Clinical Considerations: The correction rate for sodium should not exceed 10-12 mEq/L in 24 hours to prevent central pontine myelinolysis. Consider dividing the calculated deficit into portions for safer administration over 48-72 hours.
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