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  • Dr. Jordan Weinstein created a new article Test New QX
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  • Dr. Jordan Weinstein replied to a discussion, Kidney readings
    Are these the bubbles in the urine that can indicate that the kidneys are not working


    In the absence of abnormal protein levels in the urine, bubbles are not concerning.

    Dr. Jordan Weinstein
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  • Dr. Jordan Weinstein replied to a discussion, Kidney readings
    Thank you Dr Weinstein,
    I did just up-load a picture and I noticed bubbles so I guess I am wondering if I should have a blood test again before February
    Also I was reading an art about another test that they can use and said it was more...
    Thank you Dr Weinstein,
    I did just up-load a picture and I noticed bubbles so I guess I am wondering if I should have a blood test again before February
    Also I was reading an art about another test that they can use and said it was more accurate but may cost a bit more. Have heard if cystatin c test

    Thank you
    Wendy


    At a GFR below 60, the eGFR is likely accurate. The cystatin c assays and related GFR calculations are not widely available but if you have access to them, it might give you greater confidence in the reading you are getting.

    Dr. Jordan Weinstein
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  • Dr. Jordan Weinstein replied to a discussion, Kidney readings
    Hello
    These facts are interesting, I don’t have much muscle mass so I confused on establishing whether the test they use to determine if you have a kidney function disorder needs to be changed or researchers need a different formula to have...
    Hello
    These facts are interesting, I don’t have much muscle mass so I confused on establishing whether the test they use to determine if you have a kidney function disorder needs to be changed or researchers need a different formula to have proper reading My next blood work isn’t due till February of next year should I have one in between before 2019?

    Thank you for giving so much insight with these comments from you and other guest.



    Actually Wendy, at your level of kidney function (under 60 ml/min), the eGFR test does perform well. It's in patients with GFR above 60 where its accuracy has been questioned.

    Dr. Jordan Weinstein
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  • Dr. Jordan Weinstein replied to a discussion, Kidney readings
    I think that you have correctly identified some of the important limitations MDRD formula. These calculations, as you rightly point out, are population-based and do not always perform well at the extremes of body composition. In your case, since... I think that you have correctly identified some of the important limitations MDRD formula. These calculations, as you rightly point out, are population-based and do not always perform well at the extremes of body composition. In your case, since you may have more muscle mass than the average person, the formula may not perform well at all. Therefore, as you appear to have relatively normal kidney function based on your current creatinine level, I would track that number over time versus trying to compute your actual GFR. If your creatinine is unchanged over time, your kidney function is not deteriorating. The only way that statement would become untrue is if you markedly lost muscle mass and your creatinine remained the same in blood- because as you have pointed out if you're muscle mass is lower, for the same level of kidney function, your blood creatinine level should be lower as well. I would also take into account the level of urinary protein that you have, ensuring that is normal as well, to round-out the assessment.

    All of that said, you are right, screening formulas for kidney dysfunction are far from perfect.

    Dr. Jordan Weinstein
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