The Fractional Excretion of Phosphate (FEP) calculator is an essential tool for evaluating renal phosphate handling, particularly in patients with hypophosphatemia. Under normal physiological conditions, the kidneys should conserve phosphate when plasma levels are low. This calculator assists clinicians in determining whether phosphate losses are occurring through the kidneys or other routes.
In patients with hypophosphatemia:
Studies have shown that in hypophosphatemic patients, those with extrarenal causes of phosphate depletion typically have lower FEP values, while those with renal phosphate loss exhibit higher FEP values, indicating inappropriate renal excretion.
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