Kidney Failure Risk Calculator (KFRE)
Calculation Method
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Kidney failure risk equation (KFRE) Calculator
About the KFRE Calculator
The Kidney Failure Risk Equation (KFRE) Calculator is a vital tool for predicting the risk of progression to kidney failure in patients with chronic kidney disease (CKD). By utilizing key clinical variables, this calculator helps healthcare providers make informed decisions about patient management and treatment strategies.
The KFRE Calculator provides a standardized approach to assess disease progression risk in CKD patients, enabling evidence-based clinical decision-making.
Kidney Failure Risk Equation
KFRE = 1 - exp(-exp(X))
where X = (0.220 × Age) + (0.246 × Male) + (0.451 × eGFR) + (0.556 × Albuminuria) - 1.957
Kidney Disease Risk Assessment
| GFR Categories (ml/min/1.73m²) |
A1 Normal to mildly increased <30 mg/g <3 mg/mmol |
A2 Moderately increased 30-299 mg/g 3-29 mg/mmol |
A3 Severely increased ≥300 mg/g ≥30 mg/mmol |
|
|---|---|---|---|---|
| G1 | Normal or high ≥90 |
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| G2 | Mildly decreased 60-89 |
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| G3a | Mildly to moderately decreased 45-59 |
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| G3b | Moderately to severely decreased 30-44 |
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| G4 | Severely decreased 15-29 |
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| G5 | Kidney failure <15 |
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Low risk
Moderately increased risk
High risk
Very high risk
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