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Kidney failure risk equation (KFRE) Calculator

About the KFRE Calculator

The Kidney Failure Risk Equation (KFRE) Calculator is a vital tool for predicting the risk of progression to kidney failure in patients with chronic kidney disease (CKD). By utilizing key clinical variables, this calculator helps healthcare providers make informed decisions about patient management and treatment strategies.

The KFRE Calculator provides a standardized approach to assess disease progression risk in CKD patients, enabling evidence-based clinical decision-making.


Kidney Failure Risk Equation

KFRE = 1 - exp(-exp(X))
where X = (0.220 × Age) + (0.246 × Male) + (0.451 × eGFR) + (0.556 × Albuminuria) - 1.957

Kidney Failure Risk Calculator (KFRE)

Calculation Method

Urinary ACR = Urine Albumin-to-Creatinine Ratio

KFRE Results

Two-Year Risk: Please fill all values
Five-Year Risk: Please fill all values
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Kidney Disease Risk Assessment

GFR Categories
(ml/min/1.73m²)
A1
Normal to mildly increased
<30 mg/g
<3 mg/mmol
A2
Moderately increased
30-299 mg/g
3-29 mg/mmol
A3
Severely increased
≥300 mg/g
≥30 mg/mmol
G1 Normal or high
≥90
     
G2 Mildly decreased
60-89
     
G3a Mildly to moderately decreased
45-59
     
G3b Moderately to severely decreased
30-44
     
G4 Severely decreased
15-29
     
G5 Kidney failure
<15
     
Low risk
Moderately increased risk
High risk
Very high risk
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