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  1. G. Regan
  2. General Nephrology Questions
  3. Thursday, 19 April 2012
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A friend of ours discovered during a routine examination over 3 years ago that he had kidney disease.  He was the picture of health and didn't drink or smoke or take any drugs.  He is almost 65 now.  None of the doctors in this area could find out why his kidneys were failing.  He was on home dialysis for 3 years, and about a month ago received a kidney transplant and was doing great.  He had a biopsy on the kidney last week, which is routine, and he was notified today that whatever caused his kidneys to fail (nobody knows) is causing this new kidney to fail.  He was told there is some process they will start that is similar to dialysis to try to stop the progression of this kidney failure.  Wouldn't it be prudent to try to find the cause of why his body is ruining kidneys?  Is anyone aware of a case like this?  Any help would be greatly appreciated.  We were told this by his wife today because they just found out today, but he's reluctant to tell anyone, so we can't ask any more questions at this point. We had hoped someone would have had a similar problem and would be able to impart advice.  Thank you.  G. Regan  
Responses (1)
Accepted Answer Pending Moderation
Hello,

There is a very small number of renal diseases that could recur this quickly after transplant. If he high very high levels of protein in the urine after transplant which was new in onset (meaning assuming he didn't have some from any residual kidney function related to his own kidneys), then this could indeed signal the recurrence of such a disease (a severe variant of FSGS). It sounds like the procedure they are talking about is plasmapharesis, a technology that is designed to remove the immunologic factor that can lead to this disease recurring.
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