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  Wednesday, 05 February 2025
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Hi,41 year old woman. I started to notice bubbles in my urine about maybe a month and a half ago. I was eating a high protein diet. For about 4 months, I was eating 4 protein bars a day (was eating them for the fiber content) plus a high protein cereal and eating that cereal twice a day. I stopped eating the protein bars to see if the bubbles would go away. But the bubbles persisted so I went to my primary doctor. She did a rapid urine test which showed protein in the urine. My doctor sent it to the lab for complete urinalysis and to get it cultured. Surprisingly, the complete urinalysis showed no protein and no infection. I went back to my doctor a couple weeks later and she repeated the rapid urine test and it showed no protein. It also went to the lab again for complete urinalysis and once again showed no protein. My doctor also took some bloodwork. I had my bloodwork taken a few months prior and everything was normal but she repeated the bloodwork and again everything was normal.

My bun was 8
Creatinine was 0.58
EGFR was 117
Protein was 7.5

This past week I went to an urologist. She said when she thinks of bubbles in urine, she thinks of fistulas. She has low suspicion I have a fistula since I didn’t have any risk factors but I am scheduled for a kidney ultrasound. She also did a scope in the bladder and didn’t see any kidney stones or anything bad. When I asked if we could rule out protein or if additional tests such as albumin to creatinine ratio on a spot urine were needed, she assured me that the bubbles are not abnormal. I am just concerned. I did cut out the protein bars but still eating my normal protein diet which includes lots of chicken. I eat chicken or ground turkey every day, usually for both lunch and dinner.

Any advice? Do you think I need the albumin to creatinine ratio?
1 month ago
·
#3015
Accepted Answer
Hello,

Bubbles in the urine might be - as you point out - a reflection of high urinary protein. Some protein and some bubbles are normal. To rule out abnormal protein excretion you can undergo a urine albumin and protein to creatinine ratio. If normal (or if only slightly elevated) the bubbles in your urine from a proteinuria perspective are not concerning.

Dr. Jordan Weinstein
1 month ago
·
#3015
Accepted Answer
Hello,

Bubbles in the urine might be - as you point out - a reflection of high urinary protein. Some protein and some bubbles are normal. To rule out abnormal protein excretion you can undergo a urine albumin and protein to creatinine ratio. If normal (or if only slightly elevated) the bubbles in your urine from a proteinuria perspective are not concerning.

Dr. Jordan Weinstein
1 month ago
·
#3016
Thank you for your response and the information! I just felt like the urologist was dismissing me when I asked for that additional test. She told me the bubbles were normal before even doing the kidney ultrasound. But I just didn’t think she could make the assessment without further tests. In your opinion, would you push for that urine albumin and protein to creatinine ratio? Is that the same as uACR test?
1 month ago
·
#3017
It would not be unreasonable to ask for it but it will likely be normal. Yes, that is similar to the uACR test. Can combine with PCR as well.

Jordan
1 month ago
·
#3018
You are making me feel a lot better about things! These bubbles have been a constant worry for me since mid December. I think I will ask my primary doctor to order tests if she can. For the urine albumin and protein to creatinine ratio you mentioned in the first message, is there an abbreviation for that test? Even though they are similar, i want to understand all the different tests? Can this be a spot urine test? I didn’t want to do 24 hour test.
1 month ago
·
#3019
I am not sure if my previous message was received because I don’t see it here so sending my question again.

You mentioned uACR was similar to the test you initially mentioned. Is there an abbreviation to urine albumin and protein to creatinine ratio? Can this be a spot urine test? I didn’t want to do a 24 hour test.

Thanks again for your help. Talking to you has made me feel so much better already.
1 month ago
·
#3020
My pleasure,

You can albumin AND protein to creatinine ratio (ACR and PCR).

Jordan
UKidney Staff selected the reply #3015 as the answer for this post — 1 month ago
1 month ago
·
#3021
Thank you so much for your clarification!! And these can be done on a spot urine test correct?
1 month ago
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#3022
Thank you so much for your clarification!! And these can be done on a spot urine test correct?

That is correct
1 month ago
·
#3026
Hi Dr Jordan,

I am not sure if the picture with my test results was successfully submitted so I copied everything here.

Can you clarify what the results for both the ACR and PCR mean? Can we rule out proteinuria??

————

PROTEIN, TOTAL W/CREAT, RANDOM URINE    

CREATININE, RANDOM URINE
Reference Range: 20-275 mg/dL
Value :43

PROTEIN/CREATININE RATIO
Reference Range: 24-184 mg/g creat

THE PROTEIN VALUE IS LESS THAN 4 MG/DL
THEREFORE WE ARE UNABLE TO CALCULATE
EXCRETION AND/OR CREATININE RATIO.

PROTEIN/CREATININE RATIO
Reference Range: 0.024-0.184 mg/mg creat

THE PROTEIN VALUE IS LESS THAN 4 MG/DL
THEREFORE WE ARE UNABLE TO CALCULATE
EXCRETION AND/OR CREATININE RATIO.

PROTEIN, TOTAL, RANDOM UR
Reference Range: 5-24 mg/dL
Value: <4 L

Verified by repeat analysis.


ALBUMIN, RANDOM URINE W/CREATININE

CREATININE, RANDOM URINE
Reference Range: 20-275 mg/dL
Value: 43

ALBUMIN, URINE
Reference Range: Reference Range mg/dL
Not established mg/dL

Value: <0.2

ALBUMIN/CREATININE RATIO, RANDOM URINE
Reference Range: <30 mg/g creat

NOTE: The urine albumin value is less than 0.2 mg/dL therefore we are unable to calculate excretion and/or creatinine ratio.
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