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  1. Arun Thomas
  2. General Nephrology Questions
  3. Thursday, 09 March 2017
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Why do some renal transplant recipients develop ACR and some patients develop AMR? After sensitisation what factor determines whether it is ACR or AMR..?
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Accepted Answer Pending Moderation

Inadequate immunosuppression and other triggers for rejection can lead to both antibody-mediated rejection (AMR) or cellular rejection. Statistically, acute cellular rejection is more common in all scenarios. However, the presence of donor specific antibodies (DSA) - more-so than simply high levels of panel reactive antibodies - is a risk factor for AMR.

Thanks for the question!

Dr. Jordan Weinstein
  1. more than a month ago
  2. General Nephrology Questions
  3. # 1
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