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Kidney Disease: Improving Global Outcomes

KDIGO Guidelines

KDIGO publishes the leading international clinical practice guidelines for kidney disease, covering CKD, AKI, transplantation, glomerular disease, anemia, blood pressure, diabetes in CKD, and mineral bone disorder.

Skip the 200-page PDFs. Ask a focused clinical question and get a guideline-grounded answer in seconds.

Trained on publicly available KDIGO guideline content. UKidney and Docutrain do not host the original documents. Refer to kdigo.org for original publications.

Covered topics

Questions this assistant can help with

Best use: include guideline area, patient population, kidney function, comorbidities, and the decision you're making. Narrow questions map cleanly to a recommendation or rationale section.

About KDIGO

The international standard for nephrology practice.

KDIGO (Kidney Disease: Improving Global Outcomes) is an independent nonprofit established in 2003 that develops evidence-based clinical practice guidelines for kidney disease. It is recognized globally as the primary standard-setting body for nephrology, using the GRADE framework to grade evidence and recommendations. Guidelines are updated as evidence evolves, most recently with the 2024 CKD update.

CKD
Staging, risk stratification, treatment targets.
AKI
Definition, staging, prevention, management.
Transplantation
Candidate evaluation, post-transplant monitoring, immunosuppression.
Glomerular disease
Nephrotic and nephritic syndrome diagnosis and treatment.
Anemia in CKD
ESA therapy, iron management, transfusion.
Blood pressure in CKD
BP targets and antihypertensive selection.
Diabetes in CKD
Glycemic targets, drug selection, monitoring.
CKD-MBD
Phosphate management and vitamin D guidance.

Original source

FAQ

KDIGO assistant questions

What are KDIGO guidelines?

KDIGO publishes international clinical practice guidance for kidney disease, dialysis, transplantation, and related complications.

Can I ask about older and newer KDIGO publications?

Yes. Ask for the disease area and year when that distinction matters, especially when recommendations have changed.

Can the assistant provide treatment thresholds?

It can help locate thresholds and recommendation language, but dosing and treatment decisions should be checked against the original guideline and local policy.

Does this include every KDIGO document?

The assistant reflects the available trained guideline corpus. For official completeness, use KDIGO's publication library.

Are the 2024 KDIGO CKD guidelines included?

The assistant is trained on publicly available KDIGO guideline content. Ask the assistant directly about specific publications or year-specific recommendations.

How is this different from reading the KDIGO PDFs directly?

The assistant lets you ask focused clinical questions and get targeted answers rather than searching through lengthy documents. It's most useful when you have a specific patient scenario or want to locate a particular recommendation quickly.

  1.   17 May 2026
  2.   HENLE
Henle, UKidney document assistant
Henle Online

UKidney document assistant

Welcome to the Henle Assistant

Hi, I'm Henle, UKidney's AI document assistant for grounded answers in nephrology guidelines, housestaff manuals, and clinical resources. Ask in plain language and get cited answers traceable to the original source—not the open internet.

Choose a document below, then ask in plain language. Every answer is grounded in that specific source, not the open internet, so you get evidence-based responses you can trace back to the original text.

1

Pick a document

Choose any source from the library below.

2

Ask in plain language

Dosing, criteria, pathways: just type it.

3

Get a cited answer

Traceable back to the original text.

  1.   21 January 2026
  2.   Uncategorised

Kidney Donor Selection Assistant

Kidney Donor Selection Assistant

Access evidence-based kidney donor evaluation guidelines through our interactive document assistant. Choose between the KPD Protocol or KDIGO Guidelines, then ask questions in natural language to get instant answers from official clinical practice documents.

Select your preferred guideline document, then ask your question in plain language. The assistant will search the complete document to provide accurate, contextually relevant information with source references.

Chat with KPD Protocol Assistant

Ask questions about the Kidney Paired Donation Protocol for Participating Donors (2019). Get instant, evidence-based answers about donor eligibility, assessment criteria, and safety protocols.

Hint: You can ask for the assistant to respond in any language.

About the Documents

KPD Protocol: The Kidney Paired Donation Protocol for Participating Donors (2019), developed by the Canadian Blood Services' Living Donation Advisory Committee, establishes national standards for assessing and accepting living kidney donors participating in Canada's Kidney Paired Donation Program. The protocol harmonizes medical, psychosocial, and ethical criteria to ensure donor safety, optimize organ quality, and reduce interprovincial variability.

KDIGO Guidelines: The KDIGO 2017 Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors provides comprehensive, evidence-based recommendations for assessing donor candidates, informed consent, compatibility testing, preoperative management, and lifelong postdonation follow-up. It emphasizes quantitative risk assessment frameworks and evidence-based evaluation.

Both documents outline eligibility requirements, contraindications, and ongoing monitoring practices. Select your preferred guideline above to get started, or use the "Change Document" button to switch between them at any time.

Select Document Assistant

Choose which document you'd like to chat with

  1.   12 January 2026
  2.   Uncategorised

UKidney Psychosocial Resources

A comprehensive collection of research articles, community resources, and support materials for social workers, healthcare professionals, and individuals affected by kidney disease. These resources cover psychosocial aspects, mental health, caregiver support, and culturally-specific information to help provide holistic care and support.

Updated: Dec 2025

Find Resources

Search by keyword or filter by topic

Psychosocial Research

Community Resources

Race/Ethnicity/Indigenous: Research

Race/Ethnicity: Community Resources

2SLGBTQIA+ Research

UKidney Contributor

Courtney Sas

Courtney Sas

Courtney Sas is a clinical social worker at a University of Toronto affiliated hospital. She has a Masters in Bioethics and is an adjunct lecturer at the U of T Faculty of Social Work.

  1.   18 December 2025
  2.   Uncategorised
Henle, UKidney document assistant
Henle Online

UKidney nutritional assistant

AI-Powered Nutritional Guidance

Access evidence-based nutritional recommendations for nephrology patients through our AI-powered assistant. Ask questions in natural language to get instant answers sourced directly from authoritative nutritional guidelines and resources.

Our assistant helps you find specific dietary recommendations, management strategies and create meal plans without navigating lengthy documents. Whether you need guidance on protein intake, phosphorus management, fluid restrictions, or vitamin supplementation, get evidence-based answers quickly.

Simply ask your question in plain language, and the AI assistant will search through comprehensive nutritional resources to provide accurate, contextually relevant information with source references.

Sources & References

The AI assistant is trained on comprehensive nephrology nutritional guidelines and evidence-based resources from leading professional organizations and peer-reviewed publications.

  1. Nutritional guidelines and resources for nephrology patients
    Source: Comprehensive nephrology nutritional guidelines and evidence-based recommendations
  1.   04 December 2025
  2.   Uncategorised
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