I was wondering if lithium can affect your creatinine levels. For the past 5 or 6 years my creati one levels were fairly stable sometimes slightly high like .3 which the doctor put down to dehydration. To be honest I yused to be a heavy drinker so that don't surprise me. However 7 months ago I started taking lithium and noticed every blood test there was a rise in my levels of creatinine(everything else is within range) my BUN level although in range has been decreasing. Lithium seems to be the issue. Is this possible?