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  Monday, 25 October 2021
  3 Replies
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Hi, I am a 27 year old male and had a blood test.
My eGFR was 75ml/l and urea 10.1mmol/L.
I am a healthy adult with no other medical conditions and not taking any medications, non drinker and smoker. I had a high protein diet (I tend to eat primarily clean white lean meat e.g. turkey and chicken) and take part in powerlifting sports.
My other blood test results (liver function test and full blood counts) were all normal.

I had my blood test done after 8/9hours of eating, only to find out I was supposed to fast for 12 hours.

Is it possible that this small fasting window showed scewed results, or could it be an acute condition likey to be caused by something else?

I'm in the UK and we have very long wait times to see the doctor, I'm not due to have this reviewed for another 3/4 weeks and maybe another blood test for 4-8 weeks.

Any advice or knowledge would be appreciated.
2 years ago
Hi Dr Weinstein,

Thank you for your swift reply. When I have my next consultation I will be requesting my bloods to be done again as recommended.
What do you think the high urea levels show? Is this likely to indicate an underlying issue?
I see you actually used the CKD-EPi. I wouldn't be concerned unless any of the following were true:

  • this result was declining
  • you had abnormal levels of protein in he urine
  • you had a systemic disease including diabetes
  • you have high blood pressure
  • you have a family history of a heritable kidney disease

Fasting could affect the estimated GFR if you were dehydrated as a result. You can repeat these without fasting.

Dr. Jordan Weinstein
An eGFR of 75 is consistent with normal kidney function. Estimating formulas are generally validated in sick people with reduced GFR and do not perform as well in patients with presumed normal GFR, especially when using the modified MDRD formula in many eGFR calculators. The CKD-EPI formula performs better in patients with normal kidney function and is what we now use here:

Dr. Jordan Weinstein
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