I have a patient who has severe cramping on and even off dialysis. Have tried IV Levocarnitine, 50% dextrose injections, Vit E supplements, lowering blood and dialysate flows, manageable inter-dailytic weight gain. He does not have intra-dialytic hypotension. Nothing has worked so far (2 weeks). Have not tried quinine fearing the toxicity and hypertonic saline (only 3% is available here). Any suggestions?