[list] [*] It can be used to detect very low levels of albumin excretion [*] It is not confounded by urinary concentration or dilution [*] It can be used to estimate one's 24-hour albumin excretion. [/list]In many cases this simple test obviates the need to measure 24 hour protein quantities which are cumbersome and often inaccurate. The one caveat of replacing the ACR ratio for 24 hour urine protein is that this simple assay only detects albumin and not other proteins such as Bence Jones proteins, for example. In the case of other urinary proteins, one can measure a protein to creatinine ratio and this will measure all proteins, including albumin and others. Once Bence Jones proteinuria was ruled out, one could continue monitoring for the presence of albumin as a reliable indicator or proteinuric kidney disease.