UKidney's Ask the Experts

  1. Thomas
    Thomas
  2. General Nephrology Questions
  3. Friday, October 07 2016, 07:52 AM
  4.  Subscribe via email
Why is c4d staining in peritubular capillaries specific for AMR in an allograft biopsy unlike most other diseases in which glomerular staining is more important?
Responses (1)
Dr. Jordan Weinstein
Dr. Jordan Weinstein
Accepted Answer
Hello,

Rejection often involves the renal tubules with either cellular tubulitis or else the features you are referring to with C4D deposition in peritubular capillaries. There is a form of rejection that does involve the glomerulus (transplant glomerulitis) but it often accompanies more classical tubulitis. Isolated glomerulitis is more rare.

Dr. Jordan Weinstein
  • Page :
  • 1


There are no replies made for this post yet.
Be one of the first to reply to this post!
Guest
Submit Your Response
Upload files or images for this discussion by clicking on the upload button below. Supports gif,jpg,png,zip,rar,pdf,jpeg,doc,docx,xls,xlsx
• Remove Upload Files (Maximum File Size: 10 MB)
You may insert polls into your post. The poll would then appear in the post.
Vote Options