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  1. Thomas
  2. General Nephrology Questions
  3. Friday, 07 October 2016
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Why is c4d staining in peritubular capillaries specific for AMR in an allograft biopsy unlike most other diseases in which glomerular staining is more important?
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Accepted Answer Pending Moderation

Rejection often involves the renal tubules with either cellular tubulitis or else the features you are referring to with C4D deposition in peritubular capillaries. There is a form of rejection that does involve the glomerulus (transplant glomerulitis) but it often accompanies more classical tubulitis. Isolated glomerulitis is more rare.

Dr. Jordan Weinstein
  1. more than a month ago
  2. General Nephrology Questions
  3. # 1
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